7-Chloro-4,6-dimethoxy-l(3H)-isobenzofurane and Basidalin: Antibiotic Secondary Metabolites from Leucoagaricus cameifolia Gillet (Basidiomycetes)
نویسندگان
چکیده
Two antibiotic metabolites were isolated from cultures of Leucoagaricus cameifolia. Their structures were elucidated by spectroscopic methods. The first compound, 7-chloro-4,6-dim ethoxy-l(3 H)-isobenzofurane (1) had to our knowledge not been described from natural sources whereas the second, basidalin (2), is a known metabolite of L. naucina (H. Iinuma et al., 1983). 1 exhibits antibiotic activities with minimal inhibitory concentrations of 20 ^g/ml against Botrytis cinerea, the most sensitive microorganism.
منابع مشابه
furan-2(3H),1′-[2]cyclohexene]-3,4′-dione IUPAC Systematic Name: 7-Chloro-2′,4,6-trimethoxy-6′β-methylspiro[benzo- furan-2(3H),1′-[2]cyclohexene]-3,4′-dione Synonyms: (2S,4′R)-7-Chloro-2′,4,6-trimethoxy-4′-methylspiro[benzofuran-2- (3H),3′-cyclohexene]-3,6′-dione; (1′S-trans)-7-chloro-2′,4,6-trimethoxy-6′-methyl- spiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione; (+)-griseofulvin; (+)-7- chloro-4,6-dimethoxycoumaran-3-one-2-spiro-1′-(2′-methoxy-6′-methylcyclohex-
Chem. Abstr. Serv. Reg. No.: 126-07-8 Deleted CAS Nos: 8027-03-0; 8055-10-5; 3426-54-8; 11103-62-1; 24659-79-8 Chem. Abstr. Name: (1′S,6′R)-7-Chloro-2′,4,6-trimethoxy-6′-methylspiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione IUPAC Systematic Name: 7-Chloro-2′,4,6-trimethoxy-6′β-methylspiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione Synonyms: (2S,4′R)-7-Chloro-2′,4,6-trimethoxy-4′-methyl...
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